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ACLAM Webinar
CRISPR/Cas9-Mediated Genome Editing in Laboratory Animals Part 2: CRISPR/Cas9-Mediated Genome Editing of Rats, Rabbits, Pigs, and Beyond.
Date: December 5, 2024 from 12:00 – 1:30 EST
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Webinar: Thursday, December 5, 2024 / 12:00-1:30pm EST
Title: CRISPR/Cas9-Mediated Genome Editing in Laboratory Animals Part 2: CRISPR/Cas9-Mediated Genome Editing of Rats, Rabbits, Pigs, and Beyond
Speaker: Zachary Freeman, DVM, PhD
Summary: Back to CRISPR/Cas9-Mediated Genome Editing in Laboratory Webinar: Thursday, December 5, 2024 / 12:00-1:30pm EST Title: CRISPR/Cas9-Mediated Genome Editing in Laboratory Animals Part 2: CRISPR/Cas9-Mediated Genome Editing of Rats, Rabbits, Pigs, and Beyond Speaker: Zachary Freeman, DVM, PhD Summary: Genetically modified mice have been a critical component of animal research while creation of other genetically modified models any other species lagged behind. Previous transgenic technologies revolved around less efficient methods or required embryonic stem cells which are only widely available for mice. CRISPR/Cas9 has revolutionized genetically engineered animal model generation by allowing for direct manipulation of fertilizing zygotes allowing for editing of almost any species. This talk will discuss methods of generating these genetically engineered animal models. We will also review how genetically engineered larger models have many different challenges compared with mice that can impact clinical care, husbandry, and management.
Summary: Genetically modified mice have been a critical component of animal research while creation of other genetically modified models any other species lagged behind. Previous transgenic technologies revolved around less efficient methods or required embryonic stem cells which are only widely available for mice. CRISPR/Cas9 has revolutionized genetically engineered animal model generation by allowing for direct manipulation of fertilizing zygotes allowing for editing of almost any species. This talk will discuss methods of generating these genetically engineered animal models. We will also review how genetically engineered larger models have many different challenges compared with mice that can impact clinical care, husbandry, and management.